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Targeting host sialic acids in the upper respiratory tract with a broadly-acting neuraminidase to inhibit influenza virus transmission

The ongoing transmission of influenza A viruses (IAV) for the past century continues to be a burden to humans. IAV binds terminal sialic acids (SA) of sugar molecules present within the upper respiratory tract (URT) in order to successfully infect hosts. The two most common SA structures that are im...

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Detalles Bibliográficos
Autores principales: Ortigoza, Mila B., Mobini, Catherina L., Rocha, Hedy L., Bartlett, Stacey, Loomis, Cynthia A., Weiser, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312619/
https://www.ncbi.nlm.nih.gov/pubmed/37398388
http://dx.doi.org/10.1101/2023.06.02.543524