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Targeting Ras signaling excitability in cancer cells through combined inhibition of FAK and PI3K
The Ras/PI3K/ERK signaling network is frequently mutated in various human cancers including cervical cancer and pancreatic cancer. Previous studies showed that the Ras/PI3K/ERK signaling network displays features of excitable systems including propagation of activity waves, all-or-none responses, an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312644/ https://www.ncbi.nlm.nih.gov/pubmed/37398082 http://dx.doi.org/10.1101/2023.06.12.544386 |