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Targeting Ras signaling excitability in cancer cells through combined inhibition of FAK and PI3K

The Ras/PI3K/ERK signaling network is frequently mutated in various human cancers including cervical cancer and pancreatic cancer. Previous studies showed that the Ras/PI3K/ERK signaling network displays features of excitable systems including propagation of activity waves, all-or-none responses, an...

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Detalles Bibliográficos
Autores principales: Chen, Chao-Cheng, Wang, Suyang, Yang, Jr-Ming, Huang, Chuan-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312644/
https://www.ncbi.nlm.nih.gov/pubmed/37398082
http://dx.doi.org/10.1101/2023.06.12.544386

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