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Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

Chitin is an abundant biopolymer and pathogen-associated molecular pattern that stimulates a host innate immune response. Mammals express chitin-binding and chitin-degrading proteins to remove chitin from the body. One of these proteins, Acidic Mammalian Chitinase (AMCase), is an enzyme known for it...

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Detalles Bibliográficos
Autores principales: Díaz, Roberto Efraín, Ecker, Andrew K., Correy, Galen J., Asthana, Pooja, Young, Iris D., Faust, Bryan, Thompson, Michael C., Seiple, Ian B., Van Dyken, Steven J., Locksley, Richard M., Fraser, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312649/
https://www.ncbi.nlm.nih.gov/pubmed/37398339
http://dx.doi.org/10.1101/2023.06.03.542675