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Coiled-coil domains are sufficient to drive liquid-liquid phase separation of proteins in molecular models

Liquid-liquid phase separation (LLPS) is thought to be a main driving force in the formation of membraneless organelles. Examples of such organelles include the centrosome, central spindle, and stress granules. Recently, it has been shown that coiled-coil (CC) proteins, such as the centrosomal prote...

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Detalles Bibliográficos
Autores principales: Ramirez, Dominique A., Hough, Loren E., Shirts, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312653/
https://www.ncbi.nlm.nih.gov/pubmed/37398035
http://dx.doi.org/10.1101/2023.05.31.543124