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Alternative splicing is coupled to gene expression in a subset of variably expressed genes

Numerous factors regulate alternative splicing of human genes at a co-transcriptional level. However, how alternative splicing depends on the regulation of gene expression is poorly understood. We leveraged data from the Genotype-Tissue Expression (GTEx) project to show a significant association of...

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Detalles Bibliográficos
Autores principales: Karlebach, Guy, Steinhaus, Robin, Danis, Daniel, Devoucoux, Maeva, Anczuków, Olga, Sheynkman, Gloria, Seelow, Dominik, Robinson, Peter N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312658/
https://www.ncbi.nlm.nih.gov/pubmed/37398049
http://dx.doi.org/10.1101/2023.06.13.544742