Sorafenib inhibits invasion of multicellular organoids that mimic Lymphangioleiomyomatosis nodules

Lymphangioleiomyomatosis (LAM) is a debilitating, progressive lung disease with few therapeutic options, largely due to a paucity of mechanistic knowledge of disease pathogenesis. Lymphatic endothelial cells (LECs) are known to envelope and invade clusters of LAM-cells, comprising of smooth muscle α...

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Detalles Bibliográficos
Autores principales: Koc-Gunel, Sinem, Gautam, Lalit K., Calvert, Ben A., Murthy, Shubha, Harriott, Noa C., Nawroth, Janna C., Zhou, Beiyun, Krymskaya, Vera P., Ryan, Amy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312665/
https://www.ncbi.nlm.nih.gov/pubmed/37398026
http://dx.doi.org/10.1101/2023.06.12.544372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312665/
https://www.ncbi.nlm.nih.gov/pubmed/37398026
http://dx.doi.org/10.1101/2023.06.12.544372

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