Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma

Mechanistic modeling of cancers such as Medullary Thyroid Carcinoma (MTC) to emulate patient-specific phenotypes is challenging. The discovery of potential diagnostic markers and druggable targets in MTC urgently requires clinically relevant animal models. Here we established orthotopic mouse models...

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Detalles Bibliográficos
Autores principales: Gupta, Priyanka, Herring, Brendon, Kumar, Nilesh, Telange, Rahul, Garcia-Buntley, Sandra S., Caceres, Tessa W., Colantonio, Simona, Williams, Ford, Kurup, Pradeep, Carter, Angela M., Lin, Diana, Chen, Herbert, Rose, Bart, Jaskula-Sztul, Renata, Mukhtar, Shahid, Reddy, Sushanth, Bibb, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312670/
https://www.ncbi.nlm.nih.gov/pubmed/37398342
http://dx.doi.org/10.1101/2023.06.13.544755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312670/
https://www.ncbi.nlm.nih.gov/pubmed/37398342
http://dx.doi.org/10.1101/2023.06.13.544755

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