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Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma
Mechanistic modeling of cancers such as Medullary Thyroid Carcinoma (MTC) to emulate patient-specific phenotypes is challenging. The discovery of potential diagnostic markers and druggable targets in MTC urgently requires clinically relevant animal models. Here we established orthotopic mouse models...
Autores principales: | Gupta, Priyanka, Herring, Brendon, Kumar, Nilesh, Telange, Rahul, Garcia-Buntley, Sandra S., Caceres, Tessa W., Colantonio, Simona, Williams, Ford, Kurup, Pradeep, Carter, Angela M., Lin, Diana, Chen, Herbert, Rose, Bart, Jaskula-Sztul, Renata, Mukhtar, Shahid, Reddy, Sushanth, Bibb, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312670/ https://www.ncbi.nlm.nih.gov/pubmed/37398342 http://dx.doi.org/10.1101/2023.06.13.544755 |
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