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Dectin-1/CARD9-induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-Aspergillus activity in the lung

Myeloid phagocytes of the respiratory immune system, such as neutrophils, monocytes, and alveolar macrophages, are essential for immunity to Aspergillus fumigatus, the most common etiologic agent of mold pneumonia worldwide. Following engulfment of A. fumigatus conidia, fusion of the phagosome with...

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Detalles Bibliográficos
Autores principales: Aufiero, Mariano A., Shlezinger, Neta, Gjonbalaj, Mergim, Mills, Kathleen A.M., Ballabio, Andrea, Hohl, Tobias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312688/
https://www.ncbi.nlm.nih.gov/pubmed/37398416
http://dx.doi.org/10.1101/2023.06.13.544785