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A survey of CIN measures across mechanistic models

Chromosomal instability (CIN) is the persistent reshuffling of cancer karyotypes via chromosome mis-segregation during cell division. In cancer, CIN exists at varying levels that have differential effects on tumor progression. However, mis-segregation rates remain challenging to assess in human canc...

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Detalles Bibliográficos
Autores principales: Lynch, Andrew R., Bradford, Shermineh, Zhou, Amber S., Oxendine, Kim, Henderson, Les, Horner, Vanessa L., Weaver, Beth A., Burkard, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312700/
https://www.ncbi.nlm.nih.gov/pubmed/37398147
http://dx.doi.org/10.1101/2023.06.15.544840