Programmable RNA-guided endonucleases are widespread in eukaryotes and their viruses

TnpB proteins are RNA-guided nucleases that are broadly associated with IS200/605 family transposons in prokaryotes. TnpB homologs, named Fanzors, have been detected in genomes of some eukaryotes and large viruses, but their activity and functions in eukaryotes remain unknown. We searched genomes of...

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Detalles Bibliográficos
Autores principales: Jiang, Kaiyi, Lim, Justin, Sgrizzi, Samantha, Trinh, Michael, Kayabolen, Alisan, Yutin, Natalya, Koonin, Eugene V., Abudayyeh, Omar O., Gootenberg, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312701/
https://www.ncbi.nlm.nih.gov/pubmed/37398409
http://dx.doi.org/10.1101/2023.06.13.544871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312701/
https://www.ncbi.nlm.nih.gov/pubmed/37398409
http://dx.doi.org/10.1101/2023.06.13.544871

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