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Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain

Members of the OSCA/TMEM63 are mechanically activated ion channels and structures of some OSCA members have revealed the architecture of these channels and structural features that are potentially involved in mechanosensation. However, these structures are all in a similar state and information abou...

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Detalles Bibliográficos
Autores principales: Jojoa-Cruz, Sebastian, Burendei, Batuujin, Lee, Wen-Hsin, Ward, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312710/
https://www.ncbi.nlm.nih.gov/pubmed/37398040
http://dx.doi.org/10.1101/2023.06.15.545135