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Combination of Polymeric Micelle Formulation of TGFβ Receptor Inhibitors and Paclitaxel Produce Consistent Response Across Different Mouse Models of TNBC

Triple-negative breast cancer (TNBC) is notoriously difficult to treat due to the lack of targetable receptors and sometimes poor response to chemotherapy. The transforming growth factor-beta (TGFβ) family of proteins and their receptors (TGFR) are highly expressed in TNBC and implicated in chemothe...

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Detalles Bibliográficos
Autores principales: Vinod, Natasha, Hwang, Duhyeong, Fussell, Sloane Christian, Owens, Tyler Cannon, Tofade, Olaoluwa Christopher, Copling, Sage, Ramsey, Jacob D., Rädler, Patrick D., Atkins, Hannah M., Livingston, Eric E., Ezzell, J. Ashley, Sokolsky-Papkov, Marina, Yuan, Hong, Perou, Charles M., Kabanov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312717/
https://www.ncbi.nlm.nih.gov/pubmed/37398150
http://dx.doi.org/10.1101/2023.06.14.544381