Cargando…
Combination of Polymeric Micelle Formulation of TGFβ Receptor Inhibitors and Paclitaxel Produce Consistent Response Across Different Mouse Models of TNBC
Triple-negative breast cancer (TNBC) is notoriously difficult to treat due to the lack of targetable receptors and sometimes poor response to chemotherapy. The transforming growth factor-beta (TGFβ) family of proteins and their receptors (TGFR) are highly expressed in TNBC and implicated in chemothe...
Autores principales: | Vinod, Natasha, Hwang, Duhyeong, Fussell, Sloane Christian, Owens, Tyler Cannon, Tofade, Olaoluwa Christopher, Copling, Sage, Ramsey, Jacob D., Rädler, Patrick D., Atkins, Hannah M., Livingston, Eric E., Ezzell, J. Ashley, Sokolsky-Papkov, Marina, Yuan, Hong, Perou, Charles M., Kabanov, Alexander V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312717/ https://www.ncbi.nlm.nih.gov/pubmed/37398150 http://dx.doi.org/10.1101/2023.06.14.544381 |
Ejemplares similares
-
Cheminformatics-driven discovery of polymeric micelle formulations for poorly soluble drugs
por: Alves, Vinicius M., et al.
Publicado: (2019) -
High-capacity poly(2-oxazoline) formulation of TLR 7/8 agonist extends survival in a chemo-insensitive, metastatic model of lung adenocarcinoma
por: Vinod, Natasha, et al.
Publicado: (2020) -
Drug-Dependent Morphological Transitions in Spherical and Worm-Like Polymeric Micelles Define Stability and Pharmacological Performance of Micellar Drugs
por: Lim, Chaemin, et al.
Publicado: (2022) -
Synthesis of Well-Defined Gold Nanoparticles Using Pluronic: The Role of Radicals and Surfactants in Nanoparticles Formation
por: Sokolsky-Papkov, Marina, et al.
Publicado: (2019) -
Enhancing CDK4/6 inhibitor therapy for medulloblastoma using nanoparticle delivery and scRNA-seq–guided combination with sapanisertib
por: Lim, Chaemin, et al.
Publicado: (2022)