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Myosin 10 uses its MyTH4 and FERM domains differentially to support two aspects of spindle pole biology required for mitotic spindle bipolarity

Myosin 10 (Myo10) has the ability to link actin filaments to integrin-based adhesions and to microtubules by virtue of its integrin-binding FERM domain and microtubule-binding MyTH4 domain, respectively. Here we used Myo10 knockout cells to define Myo10’s contribution to the maintenance of spindle b...

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Detalles Bibliográficos
Autores principales: Yim, Yang-In, Pedrosa, Antonio, Wu, Xufeng, Chinthalapudi, Krishna, Cheney, Richard E., Hammer, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312724/
https://www.ncbi.nlm.nih.gov/pubmed/37398378
http://dx.doi.org/10.1101/2023.06.15.545002