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A trade-off between proliferation and defense in the fungal pathogen Cryptococcus at alkaline pH is controlled by the transcription factor GAT201

Cryptococcus is a fungal pathogen whose virulence relies on proliferation in and dissemination to host sites, and on synthesis of a defensive yet metabolically costly polysaccharide capsule. Regulatory pathways required for Cryptococcus virulence include a GATA-like transcription factor, Gat201, tha...

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Detalles Bibliográficos
Autores principales: Hughes, Elizabeth S., He, Zhenzhen, Ballou, Elizabeth R., Wallace, Edward W.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312749/
https://www.ncbi.nlm.nih.gov/pubmed/37398450
http://dx.doi.org/10.1101/2023.06.14.543486