Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response

BACKGROUND: Statins lower circulating low-density lipoprotein cholesterol (LDLC) levels and reduce cardiovascular disease risk. Though highly efficacious in general, there is considerable inter-individual variation in statin efficacy that remains largely unexplained. METHODS: To identify novel genes...

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Detalles Bibliográficos
Autores principales: Theusch, Elizabeth, Ting, Flora Y., Qin, Yuanyuan, Stevens, Kristen, Naidoo, Devesh, King, Sarah M., Yang, Neil, Orr, Joseph, Han, Brenda Y., Cyster, Jason G., Chen, Yii-Der I., Rotter, Jerome I., Krauss, Ronald M., Medina, Marisa W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312755/
https://www.ncbi.nlm.nih.gov/pubmed/37397985
http://dx.doi.org/10.1101/2023.06.14.544860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312755/
https://www.ncbi.nlm.nih.gov/pubmed/37397985
http://dx.doi.org/10.1101/2023.06.14.544860

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