Protein arginine methyltransferase 5 (Prmt5) localizes to chromatin loop anchors and modulates expression of genes at TAD boundaries during early adipogenesis

Protein arginine methyltransferase 5 (Prmt5) is an essential regulator of embryonic development and adult progenitor cell functions. Prmt5 expression is mis-regulated in many cancers, and the development of Prmt5 inhibitors as cancer therapeutics is an active area of research. Prmt5 functions via ef...

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Detalles Bibliográficos
Autores principales: Syed, Sabriya A., Shqillo, Kristina, Nand, Ankita, Zhan, Ye, Dekker, Job, Imbalzano, Anthony N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312757/
https://www.ncbi.nlm.nih.gov/pubmed/37398486
http://dx.doi.org/10.1101/2023.06.13.544859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312757/
https://www.ncbi.nlm.nih.gov/pubmed/37398486
http://dx.doi.org/10.1101/2023.06.13.544859

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