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PARP12 is required to repress the replication of a Mac1 mutant coronavirus in a cell and tissue specific manner

ADP-ribosyltransferases (ARTs) mediate the transfer of ADP-ribose from NAD(+) to protein or nucleic acid substrates. This modification can be removed by several different types of proteins, including macrodomains. Several ARTs, also known as PARPs, are stimulated by interferon, indicating ADP-ribosy...

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Detalles Bibliográficos
Autores principales: Kerr, Catherine M., Parthasarathy, Srivatsan, Schwarting, Nancy, O’Connor, Joseph J., Giri, Emily, More, Sunil, Orozco, Robin C., Fehr, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312760/
https://www.ncbi.nlm.nih.gov/pubmed/37398292
http://dx.doi.org/10.1101/2023.06.16.545351