Structural modeling of cytokine-receptor-JAK2 signaling complexes using AlphaFold Multimer

Homodimeric class 1 cytokine receptors include the erythropoietin (EPOR), thrombopoietin (TPOR), granulocyte colony-stimulating factor 3 (CSF3R), growth hormone (GHR), and prolactin receptors (PRLR). They are cell-surface single-pass transmembrane (TM) glycoproteins that regulate cell growth, prolif...

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Detalles Bibliográficos
Autores principales: Pogozheva, Irina D., Cherepanov, Stanislav, Park, Sang-Jun, Raghavan, Malini, Im, Wonpil, Lomize, Andrei L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312770/
https://www.ncbi.nlm.nih.gov/pubmed/37398331
http://dx.doi.org/10.1101/2023.06.14.544971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312770/
https://www.ncbi.nlm.nih.gov/pubmed/37398331
http://dx.doi.org/10.1101/2023.06.14.544971

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