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Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modelling

Schizophrenia phenotypes are suggestive of impaired cortical plasticity in the disease, but the mechanisms of these deficits are unknown. Genomic association studies have implicated a large number of genes that regulate neuromodulation and plasticity, indicating that the plasticity deficits have a g...

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Detalles Bibliográficos
Autores principales: Mäki-Marttunen, Tuomo, Blackwell, Kim T., Akkouh, Ibrahim, Shadrin, Alexey, Valstad, Mathias, Elvsåshagen, Tobjørn, Linne, Marja-Leena, Djurovic, Srdjan, Einevoll, Gaute T., Andreassen, Ole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312778/
https://www.ncbi.nlm.nih.gov/pubmed/37398070
http://dx.doi.org/10.1101/2023.06.14.544920