TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway

Cranial neural crest development is governed by positional gene regulatory networks (GRNs). Fine-tuning of the GRN components underly facial shape variation, yet how those in the midface are connected and activated remain poorly understood. Here, we show that concerted inactivation of Tfap2a and Tfa...

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Detalles Bibliográficos
Autores principales: Nguyen, Timothy T, Mitchell, Jennyfer M, Kiel, Michaela D, Jones, Kenneth L, Williams, Trevor J, Nichols, James T, Van Otterloo, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312788/
https://www.ncbi.nlm.nih.gov/pubmed/37398373
http://dx.doi.org/10.1101/2023.06.16.545376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312788/
https://www.ncbi.nlm.nih.gov/pubmed/37398373
http://dx.doi.org/10.1101/2023.06.16.545376

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