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Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data

Tumor heterogeneity is a complex and widely recognized trait that poses significant challenges in developing effective cancer therapies. In particular, many tumors harbor a variety of subpopulations with distinct therapeutic response characteristics. Characterizing this heterogeneity by determining...

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Detalles Bibliográficos
Autores principales: Wu, C., Gunnarsson, E.B., Myklebust, E.M., Köhn-Luque, A., Tadele, D.S., Enserink, J.M., Frigessi, A., Foo, J., Leder, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cornell University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312799/
https://www.ncbi.nlm.nih.gov/pubmed/37396610