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Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
Tumor heterogeneity is a complex and widely recognized trait that poses significant challenges in developing effective cancer therapies. In particular, many tumors harbor a variety of subpopulations with distinct therapeutic response characteristics. Characterizing this heterogeneity by determining...
Autores principales: | Wu, C., Gunnarsson, E.B., Myklebust, E.M., Köhn-Luque, A., Tadele, D.S., Enserink, J.M., Frigessi, A., Foo, J., Leder, K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cornell University
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312799/ https://www.ncbi.nlm.nih.gov/pubmed/37396610 |
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