Cargando…

Artificial Intelligence-based Efficacy Prediction of Phase 3 Clinical Trial for Repurposing Heart Failure Therapies

INTRODUCTION: Drug repurposing involves finding new therapeutic uses for already approved drugs, which can save costs as their pharmacokinetics and pharmacodynamics are already known. Predicting efficacy based on clinical endpoints is valuable for designing phase 3 trials and making Go/No-Go decisio...

Descripción completa

Detalles Bibliográficos
Autores principales: Zong, Nansu, Chowdhury, Shaika, Zhou, Shibo, Rajaganapathy, Sivaraman, yu, Yue, Wang, Liewei, Dai, Qiying, Bielinski, Suzette J., Chen, Yongbin, Cerhan, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312819/
https://www.ncbi.nlm.nih.gov/pubmed/37398384
http://dx.doi.org/10.1101/2023.05.25.23290531