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Artificial Intelligence-based Efficacy Prediction of Phase 3 Clinical Trial for Repurposing Heart Failure Therapies
INTRODUCTION: Drug repurposing involves finding new therapeutic uses for already approved drugs, which can save costs as their pharmacokinetics and pharmacodynamics are already known. Predicting efficacy based on clinical endpoints is valuable for designing phase 3 trials and making Go/No-Go decisio...
Autores principales: | Zong, Nansu, Chowdhury, Shaika, Zhou, Shibo, Rajaganapathy, Sivaraman, yu, Yue, Wang, Liewei, Dai, Qiying, Bielinski, Suzette J., Chen, Yongbin, Cerhan, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312819/ https://www.ncbi.nlm.nih.gov/pubmed/37398384 http://dx.doi.org/10.1101/2023.05.25.23290531 |
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