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Poor immunogenicity upon SARS-CoV-2 mRNA vaccinations in autoimmune SLE patients is associated with pronounced EF-mediated responses and anti-BAFF/Belimumab treatment

Novel mRNA vaccines have resulted in a reduced number of SARS-CoV-2 infections and hospitalizations. Yet, there is a paucity of studies regarding their effectiveness on immunocompromised autoimmune subjects. In this study, we enrolled subjects naïve to SARS-CoV-2 infections from two cohorts of healt...

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Detalles Bibliográficos
Autores principales: Faliti, Caterina E., Anam, Fabliha A., Cheedarla, Narayanaiah, Woodruff, Matthew C., Usman, Sabeena Y., Runnstrom, Martin C., Van, Trinh T.P., Kyu, Shuya, Ahmed, Hasan, Morrison-Porter, Andrea, Quehl, Hannah, Haddad, Natalie S., Chen, Weirong, Cheedarla, Suneethamma, Neish, Andrew S., Roback, John D., Antia, Rustom, Khosroshahi, Arezou, Lee, F. Eun-Hyung, Sanz, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312827/
https://www.ncbi.nlm.nih.gov/pubmed/37398319
http://dx.doi.org/10.1101/2023.06.08.23291159