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An explanation for SARS-CoV-2 rebound after Paxlovid treatment

In a fraction of SARS-CoV-2 infected individuals treated with the oral antiviral Paxlovid, the virus rebounds following treatment. The mechanism driving rebound is not understood. Here, we show that viral dynamic models based on the hypothesis that Paxlovid treatment near the time of symptom onset h...

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Detalles Bibliográficos
Autores principales: Perelson, Alan S., Ribeiro, Ruy M., Phan, Tin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312846/
https://www.ncbi.nlm.nih.gov/pubmed/37398088
http://dx.doi.org/10.1101/2023.05.30.23290747