Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights

Autoimmune hepatitis (AIH) is a severe autoimmune disease, characterized by the presence of autoantibodies. However, the role of autoantibodies in the pathophysiology of AIH remains uncertain. Here, we employed Phage Immunoprecipitation-Sequencing (PhIP-Seq) to identify novel autoantibodies in AIH....

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Detalles Bibliográficos
Autores principales: Klepper, Arielle, Kung, Andrew, Vazquez, Sara E., Mitchell, Anthea, Mann, Sabrina, Zorn, Kelsey, Avila-Vargas, Isaac, Kari, Swathi, Tekeste, Melawit, Castro, Javier, Lee, Briton, Duarte, Maria, Khalili, Mandana, Yang, Monica, Wolters, Paul, Price, Jennifer, Perito, Emily, Feng, Sandy, Maher, Jacquelyn J., Lai, Jennifer, Weiler-Normann, Christina, Lohse, Ansgar W, DeRisi, Joseph, Tana, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312872/
https://www.ncbi.nlm.nih.gov/pubmed/37398174
http://dx.doi.org/10.1101/2023.06.12.23291297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312872/
https://www.ncbi.nlm.nih.gov/pubmed/37398174
http://dx.doi.org/10.1101/2023.06.12.23291297

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