Microglial CSF1R radioligand [(11)C]CPPC as a marker of disease severity in early Parkinson’s disease: a pilot study

BACKGROUND: Enhanced innate immune response is detected in autopsy studies of Parkinson’s disease (PD) but the role of microglia in early pathophysiology is unclear. While the translocator protein 18 kDa (TSPO) that marks glial activation may be high in PD, TSPO expression is not limited to microgli...

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Detalles Bibliográficos
Autores principales: Mills, Kelly A., Du, Yong, Coughlin, Jennifer M., Horti, Andrew G., Jenkins, Katelyn, Spiro, Ergi, Motley, Chelsie S., Dannals, Robert F., Pomper, Martin G., Dawson, Ted M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312881/
https://www.ncbi.nlm.nih.gov/pubmed/37398476
http://dx.doi.org/10.1101/2023.05.28.23290647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312881/
https://www.ncbi.nlm.nih.gov/pubmed/37398476
http://dx.doi.org/10.1101/2023.05.28.23290647

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