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Microglial CSF1R radioligand [(11)C]CPPC as a marker of disease severity in early Parkinson’s disease: a pilot study
BACKGROUND: Enhanced innate immune response is detected in autopsy studies of Parkinson’s disease (PD) but the role of microglia in early pathophysiology is unclear. While the translocator protein 18 kDa (TSPO) that marks glial activation may be high in PD, TSPO expression is not limited to microgli...
Autores principales: | Mills, Kelly A., Du, Yong, Coughlin, Jennifer M., Horti, Andrew G., Jenkins, Katelyn, Spiro, Ergi, Motley, Chelsie S., Dannals, Robert F., Pomper, Martin G., Dawson, Ted M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312881/ https://www.ncbi.nlm.nih.gov/pubmed/37398476 http://dx.doi.org/10.1101/2023.05.28.23290647 |
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