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Blood RNA biomarkers for tuberculosis screening in people living with HIV prior to anti-retroviral therapy initiation: A diagnostic accuracy study

BACKGROUND: Undiagnosed tuberculosis (TB) remains a major threat for people living with HIV (PLHIV). Multiple blood transcriptomic biomarkers have shown promise for TB diagnosis. We sought to evaluate their diagnostic accuracy and clinical utility for systematic pre-antiretroviral therapy (ART) TB s...

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Detalles Bibliográficos
Autores principales: Mann, Tiffeney, Gupta, Rishi K, Reeve, Byron WP, Ndlangalavu, Gcobisa, Chandran, Aneesh, Krishna, Amirtha P, Calderwood, Claire J, Tshivhula, Happy, Palmer, Zaida, Naidoo, Selisha, Mbu, Desiree L, Theron, Grant, Noursadeghi, Mahdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312886/
https://www.ncbi.nlm.nih.gov/pubmed/37397982
http://dx.doi.org/10.1101/2023.06.01.23290783