Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target

More than 10 million people suffer from lung diseases caused by the pathogenic fungus Aspergillus fumigatus. The azole class of antifungals represent first line therapeutics for most of these infections however resistance is rising. Identification of novel antifungal targets that, when inhibited, sy...

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Detalles Bibliográficos
Autores principales: van Rhijn, Norman, Zhao, Can, Al-Furaji, Narjes, Storer, Isabelle, Valero, Clara, Gago, Sara, Chown, Harry, Baldin, Clara, Fortune-Grant, Rachael, Shuraym, Hajer Bin, Ivanova, Lia, Kniemeyer, Olaf, Krüger, Thomas, Bignell, Elaine, Goldman, Gustavo, Amich, Jorge, Delneri, Daniela, Bowyer, Paul, Brakhage, Axel, Haas, Hubertus, Bromley, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312919/
https://www.ncbi.nlm.nih.gov/pubmed/37398159
http://dx.doi.org/10.21203/rs.3.rs-2960526/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312919/
https://www.ncbi.nlm.nih.gov/pubmed/37398159
http://dx.doi.org/10.21203/rs.3.rs-2960526/v1

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