Genetic interactions between Polycystin-1 and TAZ in osteoblasts define a novel mechanosensing mechanism regulating bone formation in mice

Molecular mechanisms transducing physical forces in the bone microenvironment to regulate bone mass are poorly understood. Here, we used mouse genetics, mechanical loading, and pharmacological approaches to test the possibility that polycystin-1 and TAZ have interdependent mechanosensing functions i...

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Detalles Bibliográficos
Autores principales: Xiao, Zhousheng, Cao, Li, Smith, Micholas Dean, Li, Hanxuan, Li, Wei, Smith, Jeremy C., Quarles, Leigh Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312920/
https://www.ncbi.nlm.nih.gov/pubmed/37398127
http://dx.doi.org/10.21203/rs.3.rs-2957026/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312920/
https://www.ncbi.nlm.nih.gov/pubmed/37398127
http://dx.doi.org/10.21203/rs.3.rs-2957026/v1

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