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Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy
Acquired resistance to immune checkpoint immunotherapy remains a critical yet incompletely understood biological mechanism. Here, using a mouse model of pancreatic ductal adenocarcinoma (PDAC) to study tumor relapse following immunotherapy-induced responses, we found that tumors underwent an epithel...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312946/ https://www.ncbi.nlm.nih.gov/pubmed/37398248 http://dx.doi.org/10.21203/rs.3.rs-2960521/v1 |