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Tuning Parameters for Polygenic Risk Score Methods Using GWAS Summary Statistics from Training Data

Predicting genetic risks for common diseases may improve their prevention and early treatment. In recent years, various additive-model-based polygenic risk scores (PRS) methods have been proposed to combine the estimated effects of single nucleotide polymorphisms (SNPs) using data collected from gen...

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Detalles Bibliográficos
Autores principales:	Jiang, Wei, Chen, Ling, Girgenti, Matthew J., Zhao, Hongyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312948/ https://www.ncbi.nlm.nih.gov/pubmed/37398263 http://dx.doi.org/10.21203/rs.3.rs-2939390/v1

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