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Structure of a 10–23 Deoxyribozyme Exhibiting a Homodimer Conformation

Deoxyribozymes (DNAzymes) are in vitro evolved DNA sequences capable of catalyzing chemical reactions. The RNA cleaving 10–23 DNAzyme was the first DNAzyme to be evolved and possesses clinical and biotechnical applications as a biosensor and a knockdown agent. DNAzymes do not require the recruitment...

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Detalles Bibliográficos
Autores principales: Cramer, Evan, Starcovic, Sarah, Avey, Rebekah, Kaya, Ali, Robart, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312968/
https://www.ncbi.nlm.nih.gov/pubmed/37398199
http://dx.doi.org/10.21203/rs.3.rs-2252941/v1