Obesity-dependent increase in RalA activity disrupts mitochondrial dynamics in white adipocytes

Mitochondrial dysfunction is a characteristic trait of human and rodent obesity, insulin resistance, and fatty liver disease. Here we report that mitochondria undergo fragmentation and reduced oxidative capacity specifically in inguinal white adipose tissue after feeding mice high fat diet (HFD) by...

Descripción completa

Detalles Bibliográficos
Autores principales: xia, Wenmin, Veeragandham, Preethi, Cao, Yu, Xu, Yayun, Rhyne, Torrey, Qian, Jiaxin, Hung, Chao-Wei, Zhao, Peng, Jones, Ying, Gao, Hui, Liddle, Christopher, Yu, Ruth, Downes, Michael, Evans, Ronald, Ryden, Mikael, Wabitsch, Martin, Reilly, Shannon, Huang, Jianfeng, Saltiel, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312969/
https://www.ncbi.nlm.nih.gov/pubmed/37398165
http://dx.doi.org/10.21203/rs.3.rs-2923510/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312969/
https://www.ncbi.nlm.nih.gov/pubmed/37398165
http://dx.doi.org/10.21203/rs.3.rs-2923510/v1

Ejemplares similares