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Obesity-dependent increase in RalA activity disrupts mitochondrial dynamics in white adipocytes
Mitochondrial dysfunction is a characteristic trait of human and rodent obesity, insulin resistance, and fatty liver disease. Here we report that mitochondria undergo fragmentation and reduced oxidative capacity specifically in inguinal white adipose tissue after feeding mice high fat diet (HFD) by...
Autores principales: | xia, Wenmin, Veeragandham, Preethi, Cao, Yu, Xu, Yayun, Rhyne, Torrey, Qian, Jiaxin, Hung, Chao-Wei, Zhao, Peng, Jones, Ying, Gao, Hui, Liddle, Christopher, Yu, Ruth, Downes, Michael, Evans, Ronald, Ryden, Mikael, Wabitsch, Martin, Reilly, Shannon, Huang, Jianfeng, Saltiel, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312969/ https://www.ncbi.nlm.nih.gov/pubmed/37398165 http://dx.doi.org/10.21203/rs.3.rs-2923510/v1 |
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