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Ouabain at nanomolar concentrations is cytotoxic for biliary tract cancer cells

Biliary tract cancer is a deadly disease with limited therapeutic options. Ouabain is a well-known inhibitor of the pumping function of Na(+)/K(+)-ATPase, though there is evidence that low concentrations of ouabain lead to a reduction of cell viability of cancer cells independent of its inhibition o...

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Detalles Bibliográficos
Autores principales: Mayr, Christian, Kiesslich, Tobias, Bekric, Dino, Beyreis, Marlena, Kittl, Michael, Ablinger, Celina, Neureiter, Elen, Pichler, Martin, Prinz, Felix, Ritter, Markus, Neureiter, Daniel, Jakab, Martin, Dobias, Heidemarie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312999/
https://www.ncbi.nlm.nih.gov/pubmed/37390071
http://dx.doi.org/10.1371/journal.pone.0287769