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Ouabain at nanomolar concentrations is cytotoxic for biliary tract cancer cells
Biliary tract cancer is a deadly disease with limited therapeutic options. Ouabain is a well-known inhibitor of the pumping function of Na(+)/K(+)-ATPase, though there is evidence that low concentrations of ouabain lead to a reduction of cell viability of cancer cells independent of its inhibition o...
Autores principales: | Mayr, Christian, Kiesslich, Tobias, Bekric, Dino, Beyreis, Marlena, Kittl, Michael, Ablinger, Celina, Neureiter, Elen, Pichler, Martin, Prinz, Felix, Ritter, Markus, Neureiter, Daniel, Jakab, Martin, Dobias, Heidemarie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312999/ https://www.ncbi.nlm.nih.gov/pubmed/37390071 http://dx.doi.org/10.1371/journal.pone.0287769 |
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