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Poria cocos compounds targeting neuropeptide Y1 receptor (Y(1)R) for weight management: A computational ligand- and structure-based study with molecular dynamics simulations identified beta-amyrin acetate as a putative Y(1)R inhibitor
Poria cocos (PC) is a medicinal herb frequently used in weight-loss clinical trials, however the mechanisms by which its compounds target orexigenic receptors including the neuropeptide Y(1) receptor (Y(1)R) remain largely unknown. This study aimed to screen PC compounds for favourable pharmacokinet...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313034/ https://www.ncbi.nlm.nih.gov/pubmed/37390097 http://dx.doi.org/10.1371/journal.pone.0277873 |