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Filarial DAF-12 sense the host serum to resume iL3 development during infection

Nematode parasites enter their definitive host at the developmentally arrested infectious larval stage (iL3), and the ligand-dependent nuclear receptor DAF-12 contributes to trigger their development to adulthood. Here, we characterized DAF-12 from the filarial nematodes Brugia malayi and Dirofilari...

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Detalles Bibliográficos
Autores principales: Bétous, Rémy, Emile, Anthony, Che, Hua, Guchen, Eva, Concordet, Didier, Long, Thavy, Noack, Sandra, Selzer, Paul M., Prichard, Roger, Lespine, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313052/
https://www.ncbi.nlm.nih.gov/pubmed/37339136
http://dx.doi.org/10.1371/journal.ppat.1011462