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The cytosolic N-terminal domain of V-ATPase a-subunits is a regulatory hub targeted by multiple signals

Vacuolar H(+)-ATPases (V-ATPases) acidify several organelles in all eukaryotic cells and export protons across the plasma membrane in a subset of cell types. V-ATPases are multisubunit enzymes consisting of a peripheral subcomplex, V(1), that is exposed to the cytosol and an integral membrane subcom...

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Detalles Bibliográficos
Autores principales: Tuli, Farzana, Kane, Patricia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313074/
https://www.ncbi.nlm.nih.gov/pubmed/37398550
http://dx.doi.org/10.3389/fmolb.2023.1168680