α-Synuclein seeding activity in duodenum biopsies from Parkinson’s disease patients

Abnormal deposition of α-synuclein is a key feature and biomarker of Parkinson’s disease. α-Synuclein aggregates can propagate themselves by a prion-like seeding-based mechanism within and between tissues and are hypothesized to move between the intestine and brain. α-Synuclein RT-QuIC seed amplific...

Descripción completa

Detalles Bibliográficos
Autores principales: Vascellari, Sarah, Orrù, Christina D., Groveman, Bradley R., Parveen, Sabiha, Fenu, Giuseppe, Pisano, Giada, Piga, Giuseppe, Serra, Giulia, Oppo, Valentina, Murgia, Daniela, Perra, Andrea, Angius, Fabrizio, Hughson, Andrew G., Haigh, Cathryn L., Manzin, Aldo, Cossu, Giovanni, Caughey, Byron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313076/
https://www.ncbi.nlm.nih.gov/pubmed/37390080
http://dx.doi.org/10.1371/journal.ppat.1011456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313076/
https://www.ncbi.nlm.nih.gov/pubmed/37390080
http://dx.doi.org/10.1371/journal.ppat.1011456

Ejemplares similares