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Real-world data of pyrotinib-based therapy for patients with brain metastases of HER2-positive advanced breast cancer: a single-center retrospective analysis and molecular portraits

INTRODUCTION: Pyrotinib is a novel irreversible pan-HER tyrosine kinase inhibitor (TKI). However, real-world data of pyrotinib-containing therapy in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) and developing brain metastases (BMs) are limited, and the geno...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Liu, Qiaoyan, Zhang, Mi, Zhang, Juan, Ran, Ran, Ma, Yingying, Yang, Jiao, Wang, Fan, He, Shujuan, Zhao, Xiaoai, Wang, Le, Zhang, Lingxiao, Dong, Danfeng, Yang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313114/
https://www.ncbi.nlm.nih.gov/pubmed/37397372
http://dx.doi.org/10.3389/fonc.2023.1105474