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Molecular characterization and re-interpretation of HNF1A variants identified in Indian MODY subjects towards precision medicine

BACKGROUND: HNF1A is an essential component of the transcription factor network that controls pancreatic β-cell differentiation, maintenance, and glucose stimulated insulin secretion (GSIS). A continuum of protein malfunction is caused by variations in the HNF1A gene, from severe loss-of-function (L...

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Detalles Bibliográficos
Autores principales:	Kavitha, Babu, Ranganathan, Sampathkumar, Gopi, Sundaramoorthy, Vetrivel, Umashankar, Hemavathy, Nagarajan, Mohan, Viswanathan, Radha, Venkatesan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313120/ https://www.ncbi.nlm.nih.gov/pubmed/37396188 http://dx.doi.org/10.3389/fendo.2023.1177268

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