NOP2-mediated m5C Modification of c-Myc in an EIF3A-Dependent Manner to Reprogram Glucose Metabolism and Promote Hepatocellular Carcinoma Progression

Mitochondrial dysfunction and glycolysis activation are improtant hallmarks of hepatocellular carcinoma (HCC). NOP2 is an S-adenosyl-L-methionine-dependent methyltransferase that regulates the cell cycle and proliferation activities. In this study, found that NOP2 contributes to HCC progression by p...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Zhai, Xiangyu, Liu, Yanfeng, Xia, Zhijia, Xia, Tong, Du, Gang, Zhou, Huaxin, Franziska Strohmer, Dorothee, Bazhin, Alexandr V., Li, Ziqiang, Wang, Xianqiang, Jin, Bin, Guo, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313139/
https://www.ncbi.nlm.nih.gov/pubmed/37398932
http://dx.doi.org/10.34133/research.0184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313139/
https://www.ncbi.nlm.nih.gov/pubmed/37398932
http://dx.doi.org/10.34133/research.0184

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