Cargando…
NOP2-mediated m5C Modification of c-Myc in an EIF3A-Dependent Manner to Reprogram Glucose Metabolism and Promote Hepatocellular Carcinoma Progression
Mitochondrial dysfunction and glycolysis activation are improtant hallmarks of hepatocellular carcinoma (HCC). NOP2 is an S-adenosyl-L-methionine-dependent methyltransferase that regulates the cell cycle and proliferation activities. In this study, found that NOP2 contributes to HCC progression by p...
Autores principales: | Zhang, Hao, Zhai, Xiangyu, Liu, Yanfeng, Xia, Zhijia, Xia, Tong, Du, Gang, Zhou, Huaxin, Franziska Strohmer, Dorothee, Bazhin, Alexandr V., Li, Ziqiang, Wang, Xianqiang, Jin, Bin, Guo, Deliang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAAS
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313139/ https://www.ncbi.nlm.nih.gov/pubmed/37398932 http://dx.doi.org/10.34133/research.0184 |
Ejemplares similares
-
HMGA1 augments palbociclib efficacy via PI3K/mTOR signaling in intrahepatic cholangiocarcinoma
por: Li, Zhipeng, et al.
Publicado: (2023) -
KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc
por: Li, Jie, et al.
Publicado: (2018) -
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc–dependent manner
por: Xia, Pengyan, et al.
Publicado: (2014) -
Temporal Requirements of cMyc Protein for Reprogramming Mouse Fibroblasts
por: Heffernan, Corey, et al.
Publicado: (2012) -
The Importance of Cellular Metabolic Pathways in Pathogenesis and Selective Treatments of Hematological Malignancies
por: Soltani, Mojdeh, et al.
Publicado: (2021)