Cargando…

NOP2-mediated m5C Modification of c-Myc in an EIF3A-Dependent Manner to Reprogram Glucose Metabolism and Promote Hepatocellular Carcinoma Progression

Mitochondrial dysfunction and glycolysis activation are improtant hallmarks of hepatocellular carcinoma (HCC). NOP2 is an S-adenosyl-L-methionine-dependent methyltransferase that regulates the cell cycle and proliferation activities. In this study, found that NOP2 contributes to HCC progression by p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hao, Zhai, Xiangyu, Liu, Yanfeng, Xia, Zhijia, Xia, Tong, Du, Gang, Zhou, Huaxin, Franziska Strohmer, Dorothee, Bazhin, Alexandr V., Li, Ziqiang, Wang, Xianqiang, Jin, Bin, Guo, Deliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAAS 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313139/ https://www.ncbi.nlm.nih.gov/pubmed/37398932 http://dx.doi.org/10.34133/research.0184

Ejemplares similares

HMGA1 augments palbociclib efficacy via PI3K/mTOR signaling in intrahepatic cholangiocarcinoma
por: Li, Zhipeng, et al.
Publicado: (2023)

KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc
por: Li, Jie, et al.
Publicado: (2018)

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc–dependent manner
por: Xia, Pengyan, et al.
Publicado: (2014)

Temporal Requirements of cMyc Protein for Reprogramming Mouse Fibroblasts
por: Heffernan, Corey, et al.
Publicado: (2012)

The Importance of Cellular Metabolic Pathways in Pathogenesis and Selective Treatments of Hematological Malignancies
por: Soltani, Mojdeh, et al.
Publicado: (2021)

c-MYC responds to glucose deprivation in a cell-type-dependent manner
por: Wu, S, et al.
Publicado: (2015)

NopC/T/L Signal Crosstalk Gene GmPHT1-4
por: Zhu, Zikun, et al.
Publicado: (2023)

Burkitt’s lymphoma-associated c-Myc mutations converge on a dramatically altered target gene response and implicate Nol5a/Nop56 in oncogenesis
por: Cowling, Victoria H., et al.
Publicado: (2013)

The prognostic value of MicroRNAs associated with fatty acid metabolism in head and neck squamous cell carcinoma
por: Wang, Xiaojing, et al.
Publicado: (2022)

Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively
por: Sharma, Sunny, et al.
Publicado: (2013)

Exosomes: A potential tool for immunotherapy of ovarian cancer
por: Gong, Xiangjin, et al.
Publicado: (2023)

c-MYC Triggers Lipid Remodelling During Early Somatic Cell Reprogramming to Pluripotency
por: Prieto, Javier, et al.
Publicado: (2021)

Parkinson’s disease: no NOP, new hope
por: Arcuri, Ludovico, et al.
Publicado: (2016)

A Proteomic Screen for Nucleolar SUMO Targets Shows SUMOylation Modulates the Function of Nop5/Nop58
por: Westman, Belinda J., et al.
Publicado: (2010)

hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3
por: Wang, Xuehui, et al.
Publicado: (2021)

Runx Transcription Factors Repress Human and Murine c-Myc Expression in a DNA-Binding and C-Terminally Dependent Manner
por: Jacobs, Paejonette T., et al.
Publicado: (2013)

METTL5 stabilizes c‐Myc by facilitating USP5 translation to reprogram glucose metabolism and promote hepatocellular carcinoma progression
por: Xia, Peng, et al.
Publicado: (2023)

MUC16-mediated activation of mTOR and c-MYC reprograms pancreatic cancer metabolism
por: Shukla, Surendra K., et al.
Publicado: (2015)

c‐Myc–IMPDH1/2 axis promotes tumourigenesis by regulating GTP metabolic reprogramming
por: Zhang, Qiang, et al.
Publicado: (2023)

Translation reprogramming by eIF3 linked to glioblastoma resistance
por: Bertorello, Juliette, et al.
Publicado: (2020)

Function of m(5)C RNA methyltransferase NOP2 in high-grade serous ovarian cancer
por: Yang, Shimin, et al.
Publicado: (2023)

In vivo Reprogramming of Cancer Metabolism by MYC
por: Camarda, Roman, et al.
Publicado: (2017)

The roles of NOP56 in cancer and SCA36
por: Zhao, Shimin, et al.
Publicado: (2023)

TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition
por: Wang, Yuan, et al.
Publicado: (2020)

The SIRT2/cMYC Pathway Inhibits Peroxidation-Related Apoptosis In Cholangiocarcinoma Through Metabolic Reprogramming
por: Xu, Lei, et al.
Publicado: (2019)

Caveolin-1 inhibits breast cancer stem cells via c-Myc-mediated metabolic reprogramming
por: Wang, Shengqi, et al.
Publicado: (2020)

C-myc and N-myc in the developing brain
por: Wey, Alice, et al.
Publicado: (2010)

RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
por: George, Jasmine, et al.
Publicado: (2021)

Alternative c-MYC mRNA Transcripts as an Additional Tool for c-Myc2 and c-MycS Production in BL60 Tumors
por: Ibrahim, Dina, et al.
Publicado: (2022)

Engineered transient and stable overexpression of translation factors eIF3i and eIF3c in CHOK1 and HEK293 cells gives enhanced cell growth associated with increased c-Myc expression and increased recombinant protein synthesis
por: Roobol, Anne, et al.
Publicado: (2020)

Novel Mixed NOP/Opioid Receptor Peptide Agonists
por: Pacifico, Salvatore, et al.
Publicado: (2021)

The enterovirus genome can be translated in an IRES-independent manner that requires the initiation factors eIF2A/eIF2D
por: Kim, Hyejeong, et al.
Publicado: (2023)

Small molecule-induced epigenomic reprogramming of APL blasts leading to antiviral-like response and c-MYC downregulation
por: Amatori, Stefano, et al.
Publicado: (2022)

Archaeal fibrillarin–Nop5 heterodimer 2′-O-methylates RNA independently of the C/D guide RNP particle
por: Tomkuvienė, Miglė, et al.
Publicado: (2017)

Molecular Characterization Clinical and Immunotherapeutic Characteristics of m5C Regulator NOP2 Across 33 Cancer Types
por: Liu, Taisheng, et al.
Publicado: (2022)

eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis
por: Ruan, Hang, et al.
Publicado: (2020)

Natural killer cell-related prognosis signature characterizes immune landscape and predicts prognosis of HNSCC
por: Chi, Hao, et al.
Publicado: (2022)

C-myc/TSPEAR-AS2 Axis Facilitates Breast Cancer Growth and Metastasis in a GLUT1-Dependent Glycolysis Manner
por: Xu, Jian, et al.
Publicado: (2022)

The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in Translation Driven by Hepatitis C Virus IRES in Human Cells
por: González-Almela, Esther, et al.
Publicado: (2018)

Humanized c-Myc Mouse
por: Lehmann, Frank M., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_idvb0uk0k8jl1o683rf6ln0mle